Urinary Tract Histology
Examine these slide at low power first to find the field which best demonstrates the listed features. Label the indicated features, and briefly describe their functions. Make the following three illustrations showing the histology of the urinary tract.
HISTOLOGY IN PREPARED SLIDES: Slide 10, Kidney, injected, (H 3490), VE’s 9th: pp 250-265
I. OVERVIEW OF RENAL CORTEX at 40x:
renal capsule (if present)
medulla Here is a labeled view of the 40x kidney.
Page in Eroshenko’s Histology Atlas (VE: p. 253)
II. CLOSE-UP OF RENAL CORTEX at 400x:
glomerulus (and, if present:)
vascular pole (vessels lead in)
urinary pole (proximal tubule exits)
proximal convoluted tubules (small variable lumen, with brush borders)
distal convoluted tubules (fewer, larger lumen, without brush border)
Here is a labeled view of the 400x cortex .
Synthesizes renin in response to low blood volume or low blood pressure.
Renin then converts angiotensinogen to angiotensin.
Angiotensin stimulates the adrenal cortex to release aldosterone.
Aldosterone stimulates synthesis of Na?K pump in the ascending loop of Henle.
juxtaglomerular complex (rare to find: if present, at vascular pole)
Here is a labeled view of the juxtaglomerular complex .
And another labeled view of a juxtaglomerular complex .
and yet another labeled view of a juxtaglomerular complex!
Page in Eroshenko’s Histology Atlas (VE: pp. 255 & 257)
III. DETAILS OF RENAL MEDULLA at 400x:
None of these have RBCs in them:
loop of Henle thin segment, descending (lined with squamous cells)
loop of Henle thick segment, ascending (lined with cuboid cells)
collecting tubule (with thicker cuboid cells)* (papillary duct = its terminal portion)
Here is a labeled view of the 400x medulla .
And another labeled view of the 400x medulla contrasting the descending and ascending arms of the loop of Henle. And another contrasting the collecting tubule with the arms of the loop of Henle .
*(better seen in H150, from fall quarter)
Page in Eroshenko’s Histology Atlas (VE: p. 259)
Here are additional images of renal histology.
The nephrons in the first have been injected with dye:
Renal corpuscles, 100 x:
Renal corpuscles, 400x:
Renal medulla, 400x: